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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1979 3
1982 1
1983 3
1985 2
1987 3
1988 3
1989 3
1990 2
1991 2
1992 3
1993 1
1994 3
1995 1
1996 4
1997 3
1998 6
1999 3
2000 5
2001 5
2002 2
2003 5
2004 10
2005 4
2006 8
2007 5
2008 7
2009 9
2010 5
2011 9
2012 11
2013 8
2014 9
2015 14
2016 22
2017 23
2018 23
2019 18
2020 18
2021 36
2022 30
2023 31
2024 12

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339 results

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Page 1
A simplified guide to randomized controlled trials.
Bhide A, Shah PS, Acharya G. Bhide A, et al. Acta Obstet Gynecol Scand. 2018 Apr;97(4):380-387. doi: 10.1111/aogs.13309. Epub 2018 Feb 27. Acta Obstet Gynecol Scand. 2018. PMID: 29377058 Free article. Review.
A randomized controlled trial is a prospective, comparative, quantitative study/experiment performed under controlled conditions with random allocation of interventions to comparison groups. The randomized controlled trial is the most rigorous and robust research method of …
A randomized controlled trial is a prospective, comparative, quantitative study/experiment performed under controlled conditions with random …
Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT.
Roberts I, Shakur-Still H, Aeron-Thomas A, Beaumont D, Belli A, Brenner A, Cargill M, Chaudhri R, Douglas N, Frimley L, Gilliam C, Geer A, Jamal Z, Jooma R, Mansukhani R, Miners A, Pott J, Prowse D, Shokunbi T, Williams J. Roberts I, et al. Health Technol Assess. 2021 Apr;25(26):1-76. doi: 10.3310/hta25260. Health Technol Assess. 2021. PMID: 33928903 Free PMC article. Clinical Trial.
Patients, caregivers and those assessing outcomes were masked to allocation. All analyses were by intention to treat. We assessed the cost-effectiveness of tranexamic acid versus no treatment from a UK NHS perspective using the trial results and a Markov model. ...T …
Patients, caregivers and those assessing outcomes were masked to allocation. All analyses were by intention to treat. We assessed the …
Establishing Cost-Effective Allocation of Proton Therapy for Patients With Mediastinal Hodgkin Lymphoma.
Mailhot Vega RB, Mohammadi H, Patel SI, Holtzman AL, Lockney NA, Lynch JW, Bansal MM, Liang X, Slayton WB, Parsons SK, Hoppe BS, Mendenhall NP. Mailhot Vega RB, et al. Int J Radiat Oncol Biol Phys. 2022 Jan 1;112(1):158-166. doi: 10.1016/j.ijrobp.2021.07.1711. Epub 2021 Aug 2. Int J Radiat Oncol Biol Phys. 2022. PMID: 34348176
RESULTS: Proton therapy was not cost-effective in the base case for male ($129,000/ quality-adjusted life years [QALYs]) or female patients ($196,000/QALY). ...CONCLUSIONS: Proton therapy may be cost-effective a select minority of patients with MHL based on a …
RESULTS: Proton therapy was not cost-effective in the base case for male ($129,000/ quality-adjusted life years [QALYs]) or fe …
Diabetic Macular Edema and Diode Subthreshold Micropulse Laser: A Randomized Double-Masked Noninferiority Clinical Trial.
Lois N, Campbell C, Waugh N, Azuara-Blanco A, Maredza M, Mistry H, McAuley D, Acharya N, Aslam TM, Bailey C, Chong V, Downey L, Eleftheriadis H, Fatum S, George S, Ghanchi F, Groppe M, Hamilton R, Menon G, Saad A, Sivaprasad S, Shiew M, Steel DH, Talks JS, Doherty P, McDowell C, Clarke M; DIAMONDS Study Group. Lois N, et al. Ophthalmology. 2023 Jan;130(1):14-27. doi: 10.1016/j.ophtha.2022.08.012. Epub 2022 Aug 13. Ophthalmology. 2023. PMID: 35973593 Free article. Clinical Trial.

PURPOSE: To determine clinical effectiveness, safety, and cost-effectiveness of subthreshold micropulse laser (SML), compared with standard laser (SL), for diabetic macular edema (DME) with central retinal thickness (CRT) < 400 mum. DESIGN: Pragmatic, multicenter, al

…
PURPOSE: To determine clinical effectiveness, safety, and cost-effectiveness of subthreshold micropulse laser (SML), compared with st …
Home-based versus centre-based cardiac rehabilitation.
McDonagh ST, Dalal H, Moore S, Clark CE, Dean SG, Jolly K, Cowie A, Afzal J, Taylor RS. McDonagh ST, et al. Cochrane Database Syst Rev. 2023 Oct 27;10(10):CD007130. doi: 10.1002/14651858.CD007130.pub5. Cochrane Database Syst Rev. 2023. PMID: 37888805 Review.
There was a similar level of trial completion (RR 1.03, 95% CI 0.99 to 1.08; participants = 2638; studies = 22/comparisons = 26; low-certainty evidence) between home-based and centre-based participants. The cost per patient of centre- and home-based programmes was similar. …
There was a similar level of trial completion (RR 1.03, 95% CI 0.99 to 1.08; participants = 2638; studies = 22/comparisons = 26; low-certain …
Progressive exercise compared with best-practice advice, with or without corticosteroid injection, for rotator cuff disorders: the GRASP factorial RCT.
Hopewell S, Keene DJ, Heine P, Marian IR, Dritsaki M, Cureton L, Dutton SJ, Dakin H, Carr A, Hamilton W, Hansen Z, Jaggi A, Littlewood C, Barker K, Gray A, Lamb SE. Hopewell S, et al. Health Technol Assess. 2021 Aug;25(48):1-158. doi: 10.3310/hta25480. Health Technol Assess. 2021. PMID: 34382931 Free PMC article. Clinical Trial.
At a ceiling ratio of 20,000 per quality-adjusted life-year, injection plus best-practice advice had a 54.93% probability of being the most cost-effective treatment. LIMITATIONS: Participants and physiotherapists were not blinded to group allocation. ...Best-practic …
At a ceiling ratio of 20,000 per quality-adjusted life-year, injection plus best-practice advice had a 54.93% probability of being the most …
Supply-Side Cost-Effectiveness Thresholds: Questions for Evidence-Based Policy.
Sampson C, Zamora B, Watson S, Cairns J, Chalkidou K, Cubi-Molla P, Devlin N, García-Lorenzo B, Hughes DA, Leech AA, Towse A. Sampson C, et al. Appl Health Econ Health Policy. 2022 Sep;20(5):651-667. doi: 10.1007/s40258-022-00730-3. Epub 2022 Jun 7. Appl Health Econ Health Policy. 2022. PMID: 35668345 Free PMC article. Review.
There is growing interest in cost-effectiveness thresholds as a tool to inform resource allocation decisions in health care. ...Recent studies estimate the cost per unit of health based on average displacement or outcome elasticity. ...
There is growing interest in cost-effectiveness thresholds as a tool to inform resource allocation decisions in health care. . …
Cost-effectiveness analysis in pharmacogenomics.
Payne K, Shabaruddin FH. Payne K, et al. Pharmacogenomics. 2010 May;11(5):643-6. doi: 10.2217/pgs.10.45. Pharmacogenomics. 2010. PMID: 20415553 Free article. Review.
This is where the framework of cost-effectiveness analysis is useful. Existing systematic reviews of economic evaluations of genetic technologies have all highlighted the need to improve the quality of the economics evidence base. ...The future will see an increase …
This is where the framework of cost-effectiveness analysis is useful. Existing systematic reviews of economic evaluations of genetic …
Establishing Cost-Effective Allocation of Proton Therapy for Breast Irradiation.
Mailhot Vega RB, Ishaq O, Raldow A, Perez CA, Jimenez R, Scherrer-Crosbie M, Bussiere M, Taghian A, Sher DJ, MacDonald SM. Mailhot Vega RB, et al. Int J Radiat Oncol Biol Phys. 2016 May 1;95(1):11-18. doi: 10.1016/j.ijrobp.2016.02.031. Epub 2016 Mar 19. Int J Radiat Oncol Biol Phys. 2016. PMID: 27084617
Base-case analysis noted cost-effectiveness for proton RT in women with 1 CRF at an approximate minimum MHD of 6 Gy with a willingness-to-pay threshold of $100,000/quality-adjusted life-year. For women with 1 CRF, probabilistic sensitivity analysis noted the prefere …
Base-case analysis noted cost-effectiveness for proton RT in women with 1 CRF at an approximate minimum MHD of 6 Gy with a wil …
Surgical treatments compared with early structured physiotherapy in secondary care for adults with primary frozen shoulder: the UK FROST three-arm RCT.
Brealey S, Northgraves M, Kottam L, Keding A, Corbacho B, Goodchild L, Srikesavan C, Rex S, Charalambous CP, Hanchard N, Armstrong A, Brooksbank A, Carr A, Cooper C, Dias J, Donnelly I, Hewitt C, Lamb SE, McDaid C, Richardson G, Rodgers S, Sharp E, Spencer S, Torgerson D, Toye F, Rangan A. Brealey S, et al. Health Technol Assess. 2020 Dec;24(71):1-162. doi: 10.3310/hta24710. Health Technol Assess. 2020. PMID: 33292924 Free PMC article. Clinical Trial.
The incremental cost-effectiveness ratio for manipulation under anaesthesia was 6984 per additional quality-adjusted life-year, and this intervention was probably 86% cost-effective at the threshold of 20,000 per quality-adjusted life-year. ...Early structured physi …
The incremental cost-effectiveness ratio for manipulation under anaesthesia was 6984 per additional quality-adjusted life-year, and t …
339 results